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Publications scientifiques

Equipe CBS / CSPBAT

1.           Puljula E, Turhanen P, Vepsalainen J, Monteil M, Lecouvey M, Weisell J: Structural Requirements for Bisphosphonate Binding on Hydroxyapatite: NMR Study of Bisphosphonate Partial Esters. Acs Medicinal Chemistry Letters 2015, 6(4):397-401.

2.           Khelfallah SK, Monteil M, Deschamp J, Gager O, Migianu-Griffoni E, Lecouvey M: Synthesis of novel polymerizable molecules bearing bisphosphonate. Organic & Biomolecular Chemistry 2015, 13(46):11382-11392.

3.           Toum V, Bolley J, Lalatonne Y, Barbey C, Motte L, Lecouvey M, Royer J, Dupont N, Perard-Viret J: In silico studies, synthesis and binding evaluation of substituted 2-pyrrolidinones as peptidomimetics of RGD tripeptide sequence. European Journal of Medicinal Chemistry 2015, 93:360-372.

4.           Babouri R, Rolland M, Sainte-Catherine O, Kabouche Z, Lecouvey M, Bakalara N, Volle JN, Virieux D, Pirat JL: alpha-Halogenated oxaphosphinanes: Synthesis, unexpected reactions and evaluation as inhibitors of cancer cell proliferation. European Journal of Medicinal Chemistry 2015, 104:33-41.

5.           Cortes-Clerget M, Gager O, Monteil M, Pirat JL, Migianu-Griffoni E, Deschamp J, Lecouvey M: Novel Easily Recyclable Bifunctional Phosphonic Acid Carrying Tripeptides for the Stereoselective Michael Addition of Aldehydes with Nitroalkenes. Advanced Synthesis & Catalysis 2016, 358(1):34-40.

6.           Semerano L, Duvallet E, Belmellat N, Marival N, Schall N, Monteil M, Grouard-Vogel G, Bernier E, Lecouvey M, Hlawaty H et al: Targeting VEGF-A with a vaccine decreases inflammation and joint destruction in experimental arthritis. Angiogenesis 2016, 19(1):39-52.

7.           Kachbi-Khelfallah S, Monteil M, Cortes-Clerget M, Migianu-Griffoni E, Pirat JL, Gager O, Deschamp J, Lecouvey M: Towards potential nanoparticle contrast agents: Synthesis of new functionalized PEG bisphosphonates. Beilstein Journal of Organic Chemistry 2016, 12:1366-1371.

8.           Monteil M, Lecouvey M, Landy D, Ruellan S, Mallard I: Cyclodextrins: A promising drug delivery vehicle for bisphosphonate. Carbohydrate Polymers 2017, 156:285-293.

9.           Cortes-Clerget M, Jover J, Dussart J, Kolodziej E, Monteil M, Migianu-Griffoni E, Gager O, Deschamp J, Lecouvey M: Bifunctional Tripeptide with a Phosphonic Acid as a Bronsted Acid for Michael Addition: Mechanistic Insights. Chemistry-a European Journal 2017, 23(27):6654-6662.

10.        Linot C, Poly J, Boucard J, Pouliquen D, Nedellec S, Hulin P, Marec N, Arosio P, Lascialfari A, Guerrini A et al: PEGylated Anionic Magnetofluorescent Nanoassemblies: Impact of Their Interface Structure on Magnetic Resonance Imaging Contrast and Cellular Uptake. Acs Applied Materials & Interfaces 2017, 9(16):14242-14257.

11.        Hassani Z, Saleh A, Turpault S, Khiati S, Morelle W, Vignon J, Hugnot JP, Uro-Coste E, Legrand P, Delaforge M et al: Phostine PST3.1a Targets MGAT5 and Inhibits Glioblastoma-Initiating Cell Invasiveness and Proliferation. Molecular Cancer Research 2017, 15(10):1376-1387.

12.        Monteil M, Moustaoui H, Picardi G, Aouidat F, Djaker N, de la Chapelle ML, Lecouvey M, Spadavecchia J: Polyphosphonate ligands: From synthesis to design of hybrid PEGylated nanoparticles toward phototherapy studies. Journal of Colloid and Interface Science 2018, 513:205-213.

13.        Dussart J, Guedeney N, Deschamp J, Monteil M, Gager O, Legigan T, Migianu-Griffoni E, Lecouvey M: A convenient synthetic route towards H-bisphosphinates. Organic & Biomolecular Chemistry 2018, 16(38):6969-6979.

14.        Chniti S, Nsira A, Khouaja S, Mechria A, Gharbi R, Msaddek M, Lecouvey M: Highly diastereoselective synthesis of rigid 3-enamino-1,5-benzodiazepines. Arkivoc 2018:283-295.

15.        Dussart J, Deschamp J, Monteil M, Gager O, Migianu-Griffoni E, Lecouvey M: A General Protocol for the Synthesis of H --Hydroxyphosphinates. Synthesis-Stuttgart 2019, 51(2):421-432.

Equipe NBD / CSPBAT

16.                      Cantini F, Luzi C, Bouchemal N, Savarin P, Bozzi A, Sette M. : Effect of positive charges in the structural interaction of crabrolin isoforms with lipopolysaccharide.   J Pept Sci. 2020 Sep;26(9)

17.        Mahadeo K, Grondin I, Herbette G, Palama TL, Bouchemal N, Soulange J, Laulloo SJ, Sadeyen J, Humeau L, Frederich M, Gauvin-Bialecki A, Kodja H. : A 1H NMR-based metabolomic approach to study the production of antimalarial compounds from Psiadia arguta leaves (pers.) voigt.

Phytochemistry. 2020 Aug;176:112401

18.        Bouchemal N, Ouss L, Brassier A, Barbier V, Gobin S, Hubert L, de Lonlay P, Le Moyec L. : Diagnosis and phenotypic assessment of trimethylaminuria, and its treatment with riboflavin: 1H NMR spectroscopy and genetic testing. Orphanet J Rare Dis. 2019 Sep 18;14(1):222

Equipe LBPS / CSPBAT

19.        Falentin-Daudré C, Aitouakli M, Baumann JS, Bouchemal N, Humblot V, Migonney V, Spadavecchia J : Thiol-Poly(Sodium Styrene Sulfonate) (PolyNaSS-SH) Gold Complexes: From a Chemical Design to a One-Step Synthesis of Hybrid Gold Nanoparticles and Their Interaction with Human Proteins.  ACS Omega. 2020 Apr 2;5(14):8137-8145.

20.        Chouirfa H, Evans MDM, Castner DG, Bean P, Mercier D, Galtayries A, Falentin-Daudre C, Migonney V: Grafting of architecture controlled poly(styrene sodium sulfonate) onto titanium surfaces using bio-adhesive molecules: Surface characterization and biological properties. Biointerphases 2017, 12(2):13.

Equipe LVTS/IG

21.        Ben Mansour M, Balti R, Ollivier V, Ben Jannet H, Chaubet F, Maaroufi RM: Characterization and anticoagulant activity of a fucosylated chondroitin sulfate with unusually procoagulant effect from sea cucumber. Carbohydrate Polymers 2017, 174:760-771.

22.        Ben Mansour M, Balti R, Yacoubi L, Ollivier V, Chaubet F, Maaroufi RM: Primary structure and anticoagulant activity of fucoidan from the sea cucumber Holothuria polii. International Journal of Biological Macromolecules 2019, 121:1145-1153.

Equipe LVTS/SMBH

23.        Aufaure R, Hardouin J, Millot N, Motte L, Lalatonne Y, Guenin E: Tetrazine Click Chemistry for the Modification of 1-Hydroxy-1,1-methylenebisphosphonic Acids: Towards Bio-orthogonal Functionalization of Gold Nanoparticles. Chemistry-a European Journal 2016, 22(45):16022-16027.

Labos CSPBAT/ Anesthésie Réanimation

24.        Bakalov V, Amathieu R, Triba MN, Clement MJ, Uribe LR, Le Moyec L, Kaynar AM: Metabolomics with Nuclear Magnetic Resonance Spectroscopy in a Drosophila melanogaster Model of Surviving Sepsis. Metabolites 2016, 6(4).

Labos CSPBAT/ EREN

25.        Lécuyer L, Victor Bala A, Deschasaux M, Bouchemal N, Nawfal Triba M, Vasson M-P, Rossary A, Demidem A, Galan P, Hercberg S et al: NMR metabolomic signatures reveal predictive plasma metabolites associated with long-term risk of developing breast cancer. International Journal of Epidemiology 2018, 47(2):484-494.

Labos CSPBAT/ Hypoxie et poumon

26.        Duchemann B, Triba MN, Guez D, Rzeznik M, Savarin P, Nunes H, Valeyre D, Bernaudin JF, Le Moyec L: NUCLEAR MAGNETIC RESONANCE SPECTROSCOPIC ANALYSIS OF SALIVARY METABOLOME IN SARCOIDOSIS. Sarcoidosis Vasculitis and Diffuse Lung Diseases 2016, 33(1):10-16.

27.        Mesti T, Bouchemal N, Banissi C, Triba MN, Marbeuf-Gueye C, Cemazar M, Le Moyec L, Carpentier AF, Savarin P, Ocvirk J: Nuclear magnetic resonance metabolic fingerprint of bevacizumab in mutant IDH1 glioma cells. Radiology and Oncology 2018, 52(4):392-398.

28.        Rzeznik M, Triba MN, Levy P, Jungo S, Botosoa E, Duchemann B, Le Moyec L, Bernaudin JF, Savarin P, Guez D: Identification of a discriminative metabolomic fingerprint of potential clinical relevance in saliva of patients with periodontitis using H-1 nuclear magnetic resonance (NMR) spectroscopy. Plos One 2017, 12(8).

Labos CSPBAT/ Neurologie

29.        Mesti T, Bouchemal N, Banissi C, Triba MN, Marbeuf-Gueye C, Cemazar M, Le Moyec L, Carpentier AF, Savarin P, Ocvirk J: Nuclear magnetic resonance metabolic fingerprint of bevacizumab in mutant IDH1 glioma cells. Radiology and Oncology 2018, 52(4):392-398.

Collaborations régionales Labos CSPBAT/ UBIAE

29.        Messier FM, Le Moyec L, Santi C, Gaston AF, Triba MN, Roca E, Durand F: The impact of moderate altitude on exercise metabolism in recreational sportsmen: a nuclear magnetic resonance metabolomic approach. Applied Physiology Nutrition and Metabolism 2017, 42(11):1135-1141.

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